To help expand avoid the possibility of a placebo impact or bias in determining the effect of PFO closure on migraine rate of recurrence and severity, all sufferers were evaluated at regular monthly intervals over half a year by neurologists unaware of which group the patients had been assigned to. If PFO closure works as hoped, it could help around one in three patients with severe migraine, Dr. Wilmshurst said.. Can fixing the heart fix the relative mind? A study presented through the American University of Cardiology’s inaugural Invention in Intervention: The i2 Summit 2006 in Atlanta, Ga., will response intriguing queries about whether restoring a hole in the heart referred to as a patent foramen ovale can sooth the pain of serious migraine headaches.Related StoriesNew check for heart attack may save NHS millionsDiabetic retinopathy therapy innovations: an interview with Richard Kirk, CEO of PolyphotonixMeta-analysis backs thrombectomy over regular stroke careSince the association of selective inhibitors of COX-2 such as Vioxx, Celebrex and Bextra with an elevated incidence of coronary attack and stroke, there’s been intense interest in understanding the mechanism involved. Clarification of the chance is offered by this issue of conserving the medical benefit of these drugs for individuals with arthritis, while managing the chance, the researchers say.

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